mesenchymal stem cells (mscs) Things To Know Before You Buy
IDO is a rate-restricting enzyme for degrading tryptophan (Trp) to N-formylkynurenine. aside from the mobile–mobile Call need for MSC to induce T-mobile tolerance, the society medium also inhibits the proliferation of activated T lymphocytes, a paracrine result that partly depends on the expression of IDO.188 The IDO-mediated conversion of Trp in